SCIENTIFIC PUBLICATIONS ON BENEFITS OF CURCUMIN

1) General health beneficial properties of Curcumin

  • Anti-inflammatory, anti-viral, anti-bacterial,anti-oxidative effects (neutralise free radicals)

  • Hewlings SJ, Kalman DS. Curcumin: A Review of Its Effects on Human Health. Foods. 2017 Oct 22;6(10):92.

  • Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864.

  • Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2889-2895.

  • Jakubczyk K, Drużga A, Katarzyna J, Skonieczna-Żydecka K. Antioxidant Potential of Curcumin-A Meta-Analysis of Randomized Clinical Trials. Antioxidants (Basel). 2020;9(11):1092. Published 2020 Nov 6.

2)COVID19 Disease

  • Curcumin may prevent COVID19 and be potential treatment for COVID19.

  • Yamuna Manoharan, Vikram Haridas, K. C. Vasanthakumar, Sundaram Muthu, Fathima F. Thavoorullah, Praveenkumar Shetty. Curcumin: a Wonder Drug as a Preventive Measure for COVID19 Management.Indian J Clin Biochem. 2020 Jul; 35(3): 373–375.

  • Rocha FAC, de Assis MR. Curcumin as a potential treatment for COVID-19. Phytother Res. 2020;34(9):2085-2087.

3)Immune system and Bacterial Infections

  • Curcumin can boost the immune system and prevent bacterial infection.

  • https://www.financialexpress.com/lifestyle/health/use-power-of-turmeric-and-boost-your-immunity-with-curcumin-in-the-time-of-viral-infections/1899124/

  • Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int. 2014;2014:186864.

  • https://food.ndtv.com/health/fight-infections-and-boost-your-immunity-with-turmeric-696445.

  • Jagetia GC, Aggarwal BB. "Spicing up" of the immune system by curcumin. J Clin Immunol. 2007 Jan;27(1):19-35.

4)Tumours and different types of Cancers

  • Curcumin has anti-tumour properties and may prevent cancer.

  • Mansouri, K., Rasoulpoor, S., Daneshkhah, A. et al. Clinical effects of curcumin in enhancing cancer therapy: A systematic review. BMC Cancer 20, 791 (2020).

  • Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2889-2895.

  • Giordano A, Tommonaro G. Curcumin and Cancer. Nutrients. 2019;11(10):2376. Published 2019 Oct 5. doi:10.3390/nu11102376

  • Curcumin is effective for decreasing or preventing various cancer types including multiple myeloma and colon, pancreas, breast, prostates, and lung cancers

  • Devassy, J., Nwachukwu, I. and Jones, P. (2015). Curcumin and cancer: Barriers to obtaining a health claim. Nutr. Rev. 73(3):155–165.

  • Anand, P., Sundaram, C., Jhurani, S., Kunnumakkara, A. B. and Aggarwal, B. B. (2008). Curcumin and cancer: An “old-age” disease with an “age old”solution. Cancer Lett. 267:133–164.

  • Kocaadam-Bozkurt, Betül. (2015). Curcumin, an Active Component of Turmeric (Curcuma longa), and Its Effects on Health. Critical reviews in food science and nutrition. 57. 10.1080/10408398.2015.

5)Reproductive System

  • Curcumin can maintain and keep the reproductive system healthy.

  • https://mefirstliving.com/blogs/turmeric-benefits-and-health-news/turmeric-benefits-for-mens-reproductive-health.

  • Mohebbati R, Anaeigoudari A, Khazdair MR. The effects of Curcuma longa and curcumin on reproductive systems. Endocr Regul. 2017 Oct 26;51(4):220-228.

6)Heart, heart diseases and blood vessels health.

  • Curcumin promotes cardiovascular health and maybe cardioprotective and improve blood circulation.

  • Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2889-2895.

  • Miriyala S, Panchatcharam M, Rengarajulu P. Cardioprotective effects of curcumin. Adv Exp Med Biol. 2007;595:359-77

  • Dewar AM, Clark RA, Singer AJ, Frame MD. Curcumin mediates both dilation and constriction of peripheral arterioles via adrenergic receptors. J Invest Dermatol. 2011;131(8):1754-1760.

7)Skin health and Ageing

  • Curcumin maybe antioxidant for skin and may slow down aging.

  • Aliabbas Zia, Tahereh Farkhondeh, Ali Mohammad Pourbagher-Shahri, Saeed Samarghandian,The role of curcumin in aging and senescence: Molecular mechanisms,Biomedicine & Pharmacotherapy,Volume 134,2021,111119

8)Muscle Recovery

  • Curcumin may stimulate muscle recovery.

  • Tsai S-W, Huang C-C, Hsu Y-J, et al. Accelerated Muscle Recovery After In Vivo Curcumin Supplementation. Natural Product Communications. January 2020.

9)Bone density and Joint health

  • Curcumin may inhibit osteoporosis and relieve joints pain.

  • Hatefi M, Ahmadi MRH, Rahmani A, Dastjerdi MM, Asadollahi K. Effects of Curcumin on Bone Loss and Biochemical Markers of Bone Turnover in Patients with Spinal Cord Injury. World Neurosurg. 2018 Jun;114:e785-e791.

  • Henrotin Y, Priem F, Mobasheri A. Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management. Springerplus. 2013 Dec;2(1):56.

10)Blood Lipid profile

  • Curcumin may maintain healthy cholesterol levels and reduce cholesterol levels.

  • Yuan F, Dong H, Gong J, Wang D, Hu M, Huang W, Fang K, Qin X, Qiu X, Yang X, Lu F. A Systematic Review and Meta-analysis of Randomized Controlled Trials on the Effects of Turmeric and Curcuminoids on Blood Lipids in Adults with Metabolic Diseases. Adv Nutr. 2019 Sep 1;10(5):791-802.

  • Qin S, Huang L, Gong J, et al. Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials. Nutr J. 2017;16(1):68. Published 2017 Oct 11.

  • Marton LT, Pescinini-E-Salzedas LM, Camargo MEC, Barbalho SM, Haber JFDS, Sinatora RV, Detregiachi CRP, Girio RJS, Buchaim DV, Cincotto Dos Santos Bueno P. The Effects of Curcumin on Diabetes Mellitus: A Systematic Review. Front Endocrinol (Lausanne). 2021 May 3;12:669448.

11)Gout and blood uric acid

  • Curcumin may lower uric acid levels and reduce the risk of gout.

  • Kiyani MM, Sohail MF, Shahnaz G, et al. Evaluation of Turmeric Nanoparticles as Anti-Gout Agent: Modernization of a Traditional Drug. Medicina (Kaunas). 2019;55(1):10. Published 2019 Jan 11.

12)Diabetes and blood sugar levels

  • Curcumin may regulate blood sugar levels and maintain healthy insulin levels.

  • Pivari F, Mingione A, Brasacchio C, Soldati L. Curcumin and Type 2 Diabetes Mellitus: Prevention and Treatment. Nutrients. 2019;11(8):1837. Published 2019 Aug 8.

  • Marton LT, Pescinini-E-Salzedas LM, Camargo MEC, Barbalho SM, Haber JFDS, Sinatora RV, Detregiachi CRP, Girio RJS, Buchaim DV, Cincotto Dos Santos Bueno P. The Effects of Curcumin on Diabetes Mellitus: A Systematic Review. Front Endocrinol (Lausanne). 2021 May 3;12:669448.

13)High blood pressure or Hypertension

  • Curcumin may lower blood pressure.

  • Hadi A, Pourmasoumi M, Ghaedi E, Sahebkar A. The effect of Curcumin/Turmeric on blood pressure modulation: A systematic review and meta-analysis. Pharmacol Res. 2019 Dec;150:104505.

14)Gallbladder health

  • Curcumin may prevent gallstones formation.

  • Li Y, Li M, Wu S, Tian Y. Combination of curcumin and piperine prevents formation of gallstones in C57BL6 mice fed on lithogenic diet: whether NPC1L1/SREBP2 participates in this process?. Lipids Health Dis. 2015;14:100. Published 2015 Sep 3.

15)Liver health

  • Curcumin may be anti-fatty liver . Curcumin likely exerts beneficial effects against fatty liver disease by reducing hepatic lipid accumulation through the coordination of the AMPK/ACC pathway.

  • Liu Z., Cui C., Xu P., Dang R., Cai H., Liao D., Yang M., Feng Q., Yan X., Jiang P. Curcumin Activates AMPK Pathway and Regulates Lipid Metabolism in Rats Following Prolonged Clozapine Exposure. Front. Neurosci. 2017;11:558.

16)Kidney health and Chronic Kidney disease

  • Curcumin may help in kidney protection

  • Livia de Almeida Alvarenga, Viviane de Oliveira Leal, Natália Alvarenga Borges, Aline Silva de Aguiar, Gerd Faxén-Irving, Peter Stenvinkel, Bengt Lindholm, Denise Mafra,Curcumin - A promising nutritional strategy for chronic kidney disease patients,Journal of Functional Foods,Volume 40, 2018,Pages 715-721.

17)Menstruation

  • Curcumin may attenuate severity of premenstrual syndrome (PMS) symptoms

  • Khayat S, Fanaei H, Kheirkhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015 Jun;23(3):318-24.

18)Mood and Sleep

  • Curcumin may improve mood and induce better sleep quality.

  • Cox KHM, White DJ, Pipingas A, Poorun K, Scholey A. Further Evidence of Benefits to Mood and Working Memory from Lipidated Curcumin in Healthy Older People: A 12-Week, Double-Blind, Placebo-Controlled, Partial Replication Study. Nutrients. 2020;12(6):1678. Published 2020 Jun 4. doi:10.3390/nu12061678

  • Maghbooli M, Safarnejad B, Mostafavi H, Mazloomzadeh S, Ghoreishi A. Effect of Nanomicelle Curcumin on Quality of Life and Sleep in Patients With Parkinson’s Disease: A Double-Blind, Randomized, and Placebo-Controlled Trial. Int Clin Neurosci J [Internet]. 2019Sep.23 [cited 2021Jun.15];6(4):140-5.

19)Lungs health and disease

  • Curcumin may protect lungs.

  • Venkatesan N, Punithavathi D, Babu M. Protection from acute and chronic lung diseases by curcumin. Adv Exp Med Biol. 2007;595:379-405.

20)Cognitive function and brain disease

  • Curcumin may improve cognitive thinking and may delay or prevent Alzheimer’s disease.

  • Goozee KG, Shah TM, Sohrabi HR, Rainey-Smith SR, Brown B, Verdile G, Martins RN. Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease. Br J Nutr. 2016 Feb 14;115(3):449-65.

21)Gut Health and flora

  • Curcumin may improve gut health.

  • Scazzocchio B, Minghetti L, D'Archivio M. Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin. Nutrients. 2020;12(9):2499. Published 2020 Aug 19.

22)Neurological Diseases

  • Curcumin may prevent neurological illness and Parkinson’s disease.

  • Scazzocchio B, Minghetti L, D'Archivio M. Interaction between Gut Kulkarni SK, Dhir A. An overview of curcumin in neurological disorders. Indian J Pharm Sci. 2010 Mar;72(2):149-54.

  • Mythri RB, Bharath MM. Curcumin: a potential neuroprotective agent in Parkinson's disease. Curr Pharm Des. 2012;18(1):91-9.

23)Skin and Wound Healing

  • Curcumin may help in wound healing.

  • Akbik D, Ghadiri M, Chrzanowski W, Rohanizadeh R. Curcumin as a wound healing agent. Life Sci. 2014 Oct 22;116(1):1-7.

24)Skin diseases Eczema and Psoriasis

  • Curcumin may help in Eczema, Atopic Dermatitis and Psoriasis.

  • Panahi Y, Fazlolahzadeh O, Atkin SL, et al. Evidence of curcumin and curcumin analogue effects in skin diseases: A narrative review. Journal of Cellular Physiology. 2019 Feb;234(2):1165-1178.

  • Vollono L, Falconi M, Gaziano R, et al. Potential of Curcumin in Skin Disorders. Nutrients. 2019;11(9):2169. Published 2019 Sep 10. doi:10.

  • https://practicaldermatology.com/articles/2020-oct/turmeric-curcumin-and-curcuminoids-a-dermatologic-review/pdf

25)In Eye Diseases or in Ophthalmology.

  • Curcumin has beneficial effects on several ocular diseases, such as chronic anterior uveitis, diabetic retinopathy, glaucoma, age-related macular degeneration, and dry eye syndrome.

  • Pescosolido N, Giannotti R, Plateroti AM, Pascarella A, Nebbioso M. Curcumin: therapeutical potential in ophthalmology. Planta Med. 2014 Mar;80(4):249-54.